Endocrine Abstracts

Background: In people with HIV on ARV treatment receiving Dolutegravir (DTG)-based regimen, weight and lipodystrophy have been reported.Aim: The aim of this is to evaluate the effect of DTG on the lipid profile and fat distribution on patients who have been switched from a non to a Dolutegravir (DTG)-based regimen on the lipid profile and fat distribution.Methods: One hundred patients above 18yrs of age were recruited into two arms...

Background: The exposure to HAART has increased the chances of developing Diabetes among HIV patients. Hyperglycaemia is more common among those on Protease inhibitors (PI)-based regimens compared to other regimens. Glycated hemoglobin (HbA1c ) is now being recommended by the American Diabetes Association (ADA) for the screening of Diabetes because of convenience as it does not require fasting.Objective: We aimed to dete...

Background: The exposure to HAART has increased the chances of developing Diabetes among HIV patients. Hyperglycaemia is more common among those on Protease inhibitors (PI)-based regimens compared to other regimens. Glycated hemoglobin (HbA1c ) is now being recommended by the American Diabetes Association (ADA) for the screening of Diabetes because of convenience as it does not require fasting.Objective: We aimed to dete...

Introduction: The role of Vitamin D in bone formation and cardiovascular health could not be overemphasized. Sunlight is one of the principal sources of this vitamin/hormone. However, it’s deficiency has been observed in sunlight affluent areas. The objective of the study was to determine the prevalence and risk factors of low vitamin D among adults in the tropics (Kano).Methods: The study was a community-based cross-sectional descriptive study. The...

Background: The lipid profile of healthy adults in northern Nigeria is scarcely reported in literature. Yet, hospital records show increasing frequency of dyslipidemia-related illnesses like CVA, MI, and peripheral vascular diseases in practice. We aim to report the pattern of lipid abnormalities in a rural population in Kano, Nigeria.Methods: A population screening of apparently healthy adults resident in sub urban community in Kano was undertaken over ...

Introduction: Lipid abnormalities are very common among HIV patients particularly those on Highly Active Antiretroviral Therapy (HAART). Infection with HIV causes decline in HDL cholesterol and a raise in triglyceride. Treatment with HAART causes Dyslipidaemia in a variety of ways.Aims: To determine the prevalence and factors associated with Dyslipidaemia among HAART naïve and HAART exposed HIV patients.Methodology: Three hund...

Background: Highly active antiretroviral therapy (HAART) particularly protease inhibitors cause hyperglycaemia through insulin resistance. There is raising number of HIV patients on HAART attending the diabetic clinic in Nigeria and very few studies were done to determine their risk of developing diabetes. We aimed to determine the prevalence and factors associated with diabetes mellitus (DM) among HIV patients.Methods: In a cross sectional study of 300 ...

Background: In Nigeria, the economic burden of diabetes foot ulcer is enormous for several reasons and there are very few studies that look at the economic cost of diabetes foot care. This study estimated the cost of illness among patients with diabetes foot ulcer in secondary and tertiary health facilities in Kano.Methods: The study was a cross-sectional evaluation involving ninety patients with diabetes having various degrees of foot ulcerations. A str...

Background: Weight gain is a recognised effect of HAART which occur through restoration of the body’s immune function and lipodystrophy. Weight gain could have a negative impact on the medical and social wellbeing of the persons affected. Most HIV studies in Nigeria tend to concentrate on the effect of HAART on viral suppression and improvement in quality of life neglecting other consequences of the disease and treatment. We aimed to determine the prevalence of obesity am...